Responsibilities:

1. Develop biological information pipeline to analyze NGS data related to genome editing and gene therapy, such as targeted expander NGS, GUIDE Seq, etc.

2. Developed on the silico platform to analyze and summarize the whole genome potential goals of downstream new drug development.

3. Integrate data from various public databases and combine internally generated NGS data to enhance interpretation and visualization.

4. Responsible for the experiment schedule.

Job Requirements:

1. Master's degree in biostatistics, systems biology, computational biology, bioinformatics or related disciplines and at least two years of experience or doctor's degree.

2. Familiar with statistical methods in the context of biological systems.

3. Experience in NGS data processing and analysis using Python, Perl, C++or R.

4. Knowledge and experience in CRISPR genome editing is preferred.

5. Interested in working at the boundaries of multiple research fields and able to work in a collaborative team.

Primary Responsibilities:

1. Have experience to analyze NGS data related to genome editing ,such as amplicon NGS, GUIDE-Seq, etc.
2. Design, develop and optimize the bioinformatics analysis process and scheme
3. Develop in silico platform to profile and summarize genome-wide potential targets for downstream new drug development

Job Requirements:

1. Master degree and at least two years of experience or PhD degree in Biostatistics, Systems Biology, Computational Biology, Bioinformatics or a related discipline
2. Proficient in NGS data analysis software and process technology
3. Proficient in English reading and writing, having published English SCI search papers is preferred
4. Familiar with international mainstream biological information related database and computing tool development experience
5. Have the ability to independently engage in scientific research and communication skills.

Primary responsibilities：

1.Apply and establish necessary techniques needed in phage infection, collection, detection, propagation

2.Develop phage-assisted protein evolution platform to rewire gene editing tool

3.Provide supports in the areas of directed evolution of protein and rational engineering

4.Accountable for experiment timelines

Job Requirements：

1.A recent PhD degree in life sciences, biomedical sciences or related disciplinary

2.Experience in phage biology and evolution, protein engineering, molecular cloning, and qPCR is required

3.Experience in CRISPR or other gene editors is a plus

Responsibilities：

1. Understand the progress in the field of gene therapy, participate in the research on the research background related to gene therapy, and participate in the formulation of the company's R&D direction

2. Assist in the design and planning of the experimental scheme, implement the experimental arrangement, analyze the experimental results, regularly report the experimental progress and research results to the superior

3. Participate in optimizing the existing gene editing system, developing new gene editing related systems, and verifying the functions of new gene editing systems

4. Assist in establishing high standard gene editing process and relevant standard operation process

5. Friendly cooperation with CRO companies in the industry and good communication with external experts

Qualification:

1. Doctor degree or above, major in biology, molecular biology, biochemistry, life science, etc

2. Master the relevant knowledge and operation of CRISPR/Cas gene editing, and have knowledge in biology, biochemistry, molecular biology, neurobiology and other related disciplines

3. Have strong academic qualifications and innovation awareness, can withstand pressure, has strong work initiative and responsibility, is patient and careful, is eager to learn, has good communication, coordination ability and good team spirit

4. Relevant R&D experience in gene editing is preferred

Responsibilities:

1. With the help of scientists, complete the design of efficacy verification test plan after gene editing.

2. Responsible for the corresponding experimental scheme and technical feasibility analysis.

3. Be responsible for the preliminary preparation of the corresponding experimental scheme on consumables, reagents and platform support.

4. Responsible for routine molecular biology experiments, including nucleic acid extraction, PCR, qPCR, molecular cloning, vector construction, plasmid extraction, DNA separation and purification, protein expression and purification, ELISA, etc.

5. Improve the design of experimental research scheme, improve and optimize the experimental process.

6. According to the GLP specification and the company's file management requirements, the laboratory records and data are collated, and the operation SOP, technical report and other documents are written.

7. According to the experimental results, improve and optimize the experimental process.

Job Requirements:

1. Knowledge in biochemistry, molecular biology, biomedical engineering, pharmacy, medicine and other related disciplines;

2. Have solid molecular biology foundation, strong experimental operation ability, and the ability to analyze and solve problems; Familiar with common office software, picture analysis and data analysis software, strong English literature reading ability and certain English writing ability.

3. With strong academic qualifications and innovation awareness, able to withstand pressure, strong work initiative and responsibility, patient and careful, active and eager to learn, good communication and coordination ability and good team spirit.

Responsibilities:

1. Independently complete the design of the efficacy verification test scheme for gene editing at the cell level.

2. Responsible for the corresponding experimental scheme, technical feasibility analysis, and preliminary preparation of the corresponding experimental scheme on consumables, reagents and platform support.

3. Responsible for cell biology experiment related operations, cell culture, cell transfection, virus infection, cell freezing, immunofluorescence staining, construction of second generation library, nucleic acid extraction, PCR, qPCR.

4. Improve the design of experimental research scheme, improve and optimize the experimental process, conduct experimental records and data sorting according to GLP specifications and the company's archive management requirements, and write operation SOP, technical reports and other documents.

5. Responsible for the collection, analysis and report writing of cell biology experimental results, and improving and optimizing the experimental process according to the experimental results.

6. Technical support from relevant departments and friendly cooperation with CRO companies in the industry.

Job Requirements:

1. Bachelor degree or above in biology;

2. Knowledge in cell biology, pharmacy, bioengineering, pharmacy, medicine and other related disciplines;

3. Have a solid foundation in cell biology, strong experimental operation ability, and the ability to analyze and solve problems; Familiar with common office software, picture analysis and data analysis software, strong English literature reading ability and certain English writing ability.

4. With strong academic qualifications and innovation awareness, able to withstand pressure, strong work initiative and responsibility, patient and careful, active and eager to learn, good communication and coordination ability and good team spirit.

Main Responsibilities:

1 Participate in sorting out the test plans of pre clinical efficacy, pharmacokinetics, safety evaluation and other related studies, communicate and coordinate with CRO and other business units and management departments to ensure the project progress and research quality

2 Be responsible for tracking the analysis and processing results of research data, organizing and coordinating relevant personnel to discuss the research results, and formulating the next research content

3 Follow up the progress of the project in a timely manner and grasp the time schedule and project quality at any time

4 Cooperate with the registration applicant to collect relevant data

Job Requirement:

1 Be familiar with the information retrieval of FDA, CFDA, EMA, PMDA and other official websites of various countries, and be able to collect and sort out complete and accurate pharmacological, toxicological, pharmacokinetic and other relevant evaluation information through literature review

2 Be familiar with the detection methods or technologies related to molecular biology (WB IHC ELASA QPCR sequencing ELASA POT, etc.), and have experience in drug screening of transgenic animal models is preferred

3 Have a basic understanding of the guiding principles of drug declaration at home and abroad, and experience in drug registration and declaration is preferred

4 Be able to maintain the relationship with existing external partners and maintain good communication to ensure the smooth implementation of the project

5 According to the department's work plan, we can actively seek more external resources and ensure the smooth progress of pharmacological and toxicological research and development

Responsibilities:

1. Formulation and process development of nano liposomes.

2. Cooperate with other teams to assist in the development of ionizable cationic lipids.

3. Writing relevant literature, patent research and patented technology.

4. Independent writing and sorting of R&D reports and original records as required.

5. Other work assigned by leaders.

Job Requirements:

1. Master degree or above in materials science, pharmaceutical chemical engineering and other related majors

2. Experience in liposome nanoparticles is preferred

3. Experience in nucleic acid medicine is preferred

4. Have strong experimental operation and problem solving ability

5. Have strong learning ability and research spirit.

6. Work actively, rigorously and efficiently, with a high sense of responsibility and team spirit.

Primary responsibilities

Support the scientific operation and project management of the R&D team. Specifically, the individual will support Project Management

1. Assist project leaders to develop, validate and maintain project schedules; develop and facilitate team planning sessions

2. Manage and track contracts, timeline, cost and resources; coordinate between different projects to make team members work smoothly and efficiently

3. Anticipate, identify, and resolve discrepancies in project priorities, plans, and activities in a timely fashion

4. Coordinate regular team meeting schedules, draft agendas and provide meeting minutes, action items and progress reports according to project management best practices

5. Identify, manage and resolve issues, conflicts or risks across the projects; report promptly to whom appointed

6. Relationship management – assist project leaders and project head to manage relationship with collaborators

7. Competitive intelligence – support the gathering, organization and sharing of competitive intelligence information

Requirements

1. Minimum M.S. degree (PhD degree preferred) in biopharmaceutical science, biomedical sciences or related disciplinary

2. 3+ years of work experience in biopharma industry such as drug discovery, project management or related fields

3. Ability to leverage drug development and strong technical experience to enable robust and efficient project plan management with effective reporting and system solutions.

4. Excellent communication skills with strong business acumen

5. PPM certification is preferred

6. Experience in gene therapy is a plus

About This Job

Contract                         Full-time                             Negotiable

Master Degree               Science Park                      Middle

   3 - 5 Year

   Others

   Benefits

           · Five Day Work Week

           · Medical Plan

           · Dental Plan

           · Double Pay

           · Project Bonus

           · Performance Bonus

Primary responsibilities:

1. Develop bioinformatic pipelines to analyze NGS data related to genome editing and gene therapy

2. Develop in silico platform to profile and summarize genome-wide potential targets for gene editing

3. Integrate data from various public databases combined with in-house generated data for enhanced interpretation and visualization

4. Accountable for experiment timelines

Requirements:

1. A recent master degree/PhD degree in bioinformatics, computer science, mathematics, statistics, physics, or equivalent disciplinary

2. Knowledge of scripting or programming languages such as Python, R, and PERL, and experience in Linux system is required

3. Publications showing competence in bioinformatics is required.

4. General knowledge or experience in genomic NGS data analysis is a plus

*Only for Senior Scientist

Application process

Applicants should send a cover letter outlining their background and a CV. Interviews will start when applications are received until the position is filled. Personal data collected will be used for recruitment purposes only. Competitive compensation package will be provided for the successful candidates.

Company profile

GenEditBio is a biotech startup company aiming to provide potentially curative gene editing-based solutions for genetic diseases that have no cures or lack simple treatments today. GenEditBio is formed by a group of scientists and entrepreneurs who are passionate in gene editing-based approaches to treat diseases rooted in altered DNA bases or chromosomal structures. At GenEditBio, we develop leading-edge technologies for safe and precise gene editing, towards clinically viable gene therapies.

About This Job

Contract                                          Full-time                                          Negotiable

Doctorate Degree or Above          Science Park                                   Middle  

   < 3 Year

   Biomedical/ Biotechnology/ Bioinformatics

           Clinical Research Organisation, Molecular diagnostics, Pharmaceutics, Postdoctoral Researcher (Biomedical/ Life Science), Pharmaceutical

   Benefits

           · Five Day Work Week

           · Medical Plan

           · Dental Plan

           · Double Pay

           · Project Bonus

           · Performance Bonus

GenEditBio Limited

We are seeking a Research Associate /Research Scientist (Molecular Biology) to join our Precise Genome Editing team. You will assist with the development and validation of a genome editing method utilising CRISPR-cas9 and NGS technology.

Responsibilities

1. Design, execute and document laboratory work and experiments such as RNP transfection and NGS library preparation

2. Optimize and troubleshoot experimental protocols

3. Plan R&D work according to time frame and report experimental progress to supervisors regularly

4. Ensuring all work is performed in compliance with Good Laboratory Practice (GLP)

Essential

1. A MSc degree in Molecular Biology, biological science or a relevant scientific discipline. Bsc with R&D experience will also be considered

2. Hands-on experience in mammalian cell culture, RNP transfection and PCR

3. A good understanding of NGS libraries preparation, preferably Illumina's platform

4. Good liquid handling skill

5. Strong team player with good communication skills

6. High attention to detail

Desirable

1. Experience in CRISPR genome editing

2. Ability to use online genomic databases and resources such as NCBI or Ensembl genome browser for experimental and oligo design

About This Job

Contract               Full-time                 Negotiable

Master Degree     Science Park          Entry  

  < 3 Year

  Science/Lab

Laboratory, Life Science, Research & Development